Whole genome sequencing and genetic analysis of exopolysaccharide producing Marine bacterium P. a. Hao2018

Abstract

Our research group is committed to the prevention and control of Marine microorganisms. Recently, we isolated the seedling panel of a plant with the ability to produce good biological active exopolysaccharides P.a. Hao2018 (Leclercia peneumoniae), from the perspective of genome, genome means help us to find that genetic information, gene function, genome structure and other aspects of information mining, help us establish a system of biological evolution and phylogenetic research. Through whole genome sequencing and comparative genomics analysis of the bacteria, based on the functional characteristics of the nine LeKe species, we found that these species do not have the degradation of aromatic compounds in the phenol degradation pathway. Meanwhile, in the carbon source metabolism, these species do not metabolize pyruvate and alcohol, Leclercia sp.LTM01、Leclercia sp. EMC 7 is also unable to perform lactate metabolism, but they are connected through other carbon source metabolic pathways to jointly regulate carbon source utilization within organisms. The genus Lecella is a class of bacteria widely found in nature with certain pathogenicity and antibiotic resistance. The bacterium adapts to the host microenvironment in several ways, possibly acquiring resistance genes through phage horizontal gene transfer. Studies have found that this bacterium may also play an important role in biogeochemical cycles. In general, through whole genome sequencing and analysis, basic data support can be provided for further research on the diversity, environmental impact, material degradation and infection prevention and control of the bacterium, which is helpful to deepen the understanding and prevention and control of the bacterium.